BDBM50132329 2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)ethanol::2-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-phenyl}-ethanol::CHEMBL320417

SMILES COc1cccc(c1)-c1cn(-c2ccc(CCO)cc2)c2ncnc(N)c12

InChI Key InChIKey=PRDZKYMHQSMGSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132329   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132329(2-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]p...)
Affinity DataIC50: 1.15E+3nMAssay Description:In vitro inhibition of Src protein tyrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132329(2-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132329(2-{4-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of c-Src kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article