BDBM50129483 4-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3-pyrrolidin-1-ylmethyl-1H-indol-4-yl]-ureido}-3-(3,4-difluoro-phenyl)-propionylamino]-N-(2-pyrrolidin-1-yl-ethyl)-butyramide::CHEMBL70013

SMILES NCC[C@H](NC(=O)[C@H](Cc1ccc(F)c(F)c1)NC(=O)Nc1cccc2n(Cc3c(Cl)cccc3Cl)cc(CN3CCCC3)c12)C(=O)NCCN1CCCC1

InChI Key InChIKey=SSFAFRVEKKGDMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129483   

TargetProteinase-activated receptor 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50129483(4-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3-pyr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Ability to inhibit the binding of [3H]S-(p-F-Phe)-homoarginine-L-homoarginine-KY-NH2 to thrombin receptor on the membranes of CHRF-288-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed