BDBM50129357 2-(3-Benzyl-ureido)-benzothiazole-6-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL305249

SMILES Cc1cc(C)c(NC(=O)c2ccc3nc(NC(=O)NCc4ccccc4)sc3c2)c(C)c1

InChI Key InChIKey=OPSZHFXGDMKFKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129357   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50129357(2-(3-Benzyl-ureido)-benzothiazole-6-carboxylic aci...)
Affinity DataIC50: 1.73E+3nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed