BDBM50129340 4-[(2-tert-Butoxycarbonylamino-benzothiazole-6-carbonyl)-amino]-3,5-dimethyl-benzoic acid methyl ester::CHEMBL67987

SMILES COC(=O)c1cc(C)c(NC(=O)c2ccc3nc(NC(=O)OC(C)(C)C)sc3c2)c(C)c1

InChI Key InChIKey=VNVPVQWVVYAZRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129340   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50129340(4-[(2-tert-Butoxycarbonylamino-benzothiazole-6-car...)
Affinity DataIC50: 3.12E+3nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed