BDBM50129197 4-(Hydroxyamino)-4-oxobutanoic acid::CHEMBL51979::N-Hydroxy-succinamic acid

SMILES ONC(=O)CCC(O)=O

InChI Key InChIKey=AGEUQNZXCIVHPB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50129197   

TargetGlutamate carboxypeptidase 2(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of Glutamate carboxypeptidase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181-426) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGamma-butyrobetaine dioxygenase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BBOX1 by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human FIH expressed in Escherichia coli by MALDI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 2A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50129197(N-Hydroxy-succinamic acid | 4-(Hydroxyamino)-4-oxo...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed