BDBM50129125 CHEMBL3629245::US10434085, Compound 6

SMILES COc1cc2\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c2c(O)c1Br

InChI Key InChIKey=IQNPHDUBVHLQRF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129125   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
University of North Carolina At Greensboro

Curated by ChEMBL

LigandBDBM50129125(CHEMBL3629245 | US10434085, Compound 6)Copy SMILESCopy InChI

Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/16/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetMitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1(Human)
University of North Carolina At Greensboro

US Patent

LigandBDBM50129125(CHEMBL3629245 | US10434085, Compound 6)Copy SMILESCopy InChI

Affinity DataIC50: 2.60E+3nMAssay Description:The assay was performed at BSP Biosience Inc. (5Z)-7-oxozeaenol was used as a positive control. Analogue 3 was not tested due to the short-term stabi...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL