BDBM50126803 8-(4-Chloro-phenyl)-3-aza-bicyclo[3.2.1]octane::CHEMBL34955

SMILES Clc1ccc(cc1)C1C2CCC1CNC2

InChI Key InChIKey=DQTXEZQCBHGHHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126803   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126803(8-(4-Chloro-phenyl)-3-aza-bicyclo[3.2.1]octane | C...)
Affinity DataIC50: 478nMAssay Description:Inhibition of [3H]DA binding to DAT in rat striatal synaptosomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126803(8-(4-Chloro-phenyl)-3-aza-bicyclo[3.2.1]octane | C...)
Affinity DataIC50: 81.5nMAssay Description:Inhibition of [3H]WIN-35428 binding to the cocaine binding site on the dopamine transporter (DAT) in synaptosomal membrane preparations from rat stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50126803(8-(4-Chloro-phenyl)-3-aza-bicyclo[3.2.1]octane | C...)
Affinity DataIC50: 363nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter (5-HTT) in rat cortical tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed