BDBM50126412 CHEMBL30642::N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-yl]-N,N'-dimethyl-propane-1,3-diamine

SMILES CNCCCN(C)c1nc(cc2ncccc12)-c1ccc(cc1)N(C)C

InChI Key InChIKey=LXPMHXBLTCVBRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126412   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126412(N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 890nMAssay Description:Inhibitory activity against spleen tyrosine kinase (SYK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126412(N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 890nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed