BDBM50126411 CHEMBL284675::N*1*-[7-(4-Methoxy-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine::N1-(7-(4-methoxyphenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine

SMILES COc1ccc(cc1)-c1cc2ncccc2c(NCCCN)n1

InChI Key InChIKey=XDWDNVGQYUIZEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126411   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126411(N*1*-[7-(4-Methoxy-phenyl)-[1,6]naphthyridin-5-yl]...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against spleen tyrosine kinase (SYK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126411(N*1*-[7-(4-Methoxy-phenyl)-[1,6]naphthyridin-5-yl]...)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126411(N*1*-[7-(4-Methoxy-phenyl)-[1,6]naphthyridin-5-yl]...)
Affinity DataIC50: 140nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed