BDBM50126410 CHEMBL30548::N*1*-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-yl]-N*1*-methyl-propane-1,3-diamine::N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-yl)-N1-methylpropane-1,3-diamine

SMILES CN(C)c1ccc(cc1)-c1cc2ncccc2c(n1)N(C)CCCN

InChI Key InChIKey=WFMQFWSNRYPUHL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126410   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126410(N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against spleen tyrosine kinase (SYK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126410(N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126410(N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 72nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126410(N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 72nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed