BDBM50126142 4-Phenylimidazole::CHEMBL14145::US11053207, Compound 5-phenyl-1-imidazole(control)
SMILES c1ncc([nH]1)-c1ccccc1
InChI Key InChIKey=XHLKOHSAWQPOFO-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50126142
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human IDO expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of kynurenine production using L-tryptophan as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+4nMAssay Description:Firstly, the compound was subject to a 3-fold gradient dilution. 1 μL of each concentration was added to a 96-well plate; 50 μL of the IDO ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+5nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human IDO1 using L-tryptophan as substrate assessed as reduction in N-formyl kynurenine formation by UV-visible spectroscopic analysisMore data for this Ligand-Target Pair