BDBM50125921 CHEMBL21910::N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-(4-methoxyphenyl)acetamide::N-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-(4-methoxy-phenyl)-acetamide

SMILES COc1ccc(CC(=O)Nc2nc3nn(C)c(SC)c3c3nc(nn23)-c2ccco2)cc1

InChI Key InChIKey=BUPXLNFYXPSBGC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50125921   

TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50125921(N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyraz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50125921(N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyraz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]- SCH-58261 binding at human Adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125921(N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyraz...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]- DPCPX from human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125921(N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyraz...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]- DPCPX binding at human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50125921(N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyraz...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50125921(N-(2-(furan-2-yl)-8-methyl-9-(methylthio)-8H-pyraz...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]- MRE 308F20 binding from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed