BDBM50125911 1-(9-Ethylamino-2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea::CHEMBL20555::CHEMBL554955

SMILES CCNc1n(C)nc2nc(NC(=O)Nc3ccc(OC)cc3)n3nc(nc3c12)-c1ccco1

InChI Key InChIKey=HVOOLKXFKGSNFT-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50125911   

TargetAdenosine receptor A3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity as inhibition of cAMP generation after agonist-modulation of Adenosine A3 receptor with 100 nM CI-IB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataIC50: 61nMAssay Description:Antagonist activity as inhibition of cAMP generation after agonist-modulation of human Adenosine A2A receptor with 100 nM NECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]- MRE 308F20 binding from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]- MRE 308F20 binding from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]- SCH-58261 binding at human Adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]- SCH-58261 binding at human Adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]- DPCPX from human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]- DPCPX from human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]- DPCPX binding at human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50125911(CHEMBL554955 | CHEMBL20555 | 1-(9-Ethylamino-2-fur...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]- DPCPX binding at human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed