BDBM50125457 3-(3-Hydroxymethyl-phenyl)-1-[2-(3-hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-1H-pyridin-2-one::CHEMBL429211

SMILES OCc1cccc(c1)-c1cccn(C(CN2CCC(O)C2)c2ccccc2)c1=O

InChI Key InChIKey=CZIDHILBPYABIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125457   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125457(3-(3-Hydroxymethyl-phenyl)-1-[2-(3-hydroxy-pyrroli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]deltorphin binding to human delta opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125457(3-(3-Hydroxymethyl-phenyl)-1-[2-(3-hydroxy-pyrroli...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of [125I]Enkephalin binding to human mu opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125457(3-(3-Hydroxymethyl-phenyl)-1-[2-(3-hydroxy-pyrroli...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed