BDBM50125455 1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3-(3-trifluoromethoxy-phenyl)-1H-pyridin-2-one::CHEMBL278062

SMILES OC1CCN(CC(c2ccccc2)n2cccc(-c3cccc(OC(F)(F)F)c3)c2=O)C1

InChI Key InChIKey=YURULKGWGZYSBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50125455   

TargetDelta-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125455(1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]deltorphin binding to human delta opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125455(1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50125455(1-[2-(3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-3...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of [125I]Enkephalin binding to human mu opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed