BDBM50125101 Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-azepino[4,3,2-cd]indole-6-carbonyl)-phenyl]-amide::CHEMBL165670

SMILES O=C(Nc1ccc(cc1)C(=O)N1CCCc2c[nH]c3cccc1c23)c1ccccc1-c1ccccc1

InChI Key InChIKey=OIOWQZHYLNNEAS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125101   

TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity of the human V2 receptor was assessed by the accumulation of cAMP in transfected HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVasopressin V1a receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Binding affinity towards VIa receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVasopressin V2 receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50: 1nMAssay Description:Binding affinity towards V2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVasopressin V2 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125101(Biphenyl-2-carboxylic acid [4-(1,3,4,5-tetrahydro-...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]AVP from human V2 receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed