BDBM50124914 CHEMBL161180::N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzamidine

SMILES NC(=NCc1cc(Cl)cc(Cl)c1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=HCUDNPNQOOAXTQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50124914   

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2A subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataIC50: 24nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(N-(3,5-Dichloro-benzyl)-4-trifluoromethoxy-benzami...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed