BDBM50124518 (E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)-acrylic acid::(E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]cinnamic acid::CHEMBL442016

SMILES OC(=O)\C=C\c1ccc(cc1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=QAWBIEIZDDIEMW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124518   

TargetRetinoic acid receptor beta(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50124518((E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]cinnamic ac...)
Affinity DataEC50:  200nMAssay Description:Effective concentration against retinoic acid receptor beta in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (0.1-0.3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPup--protein ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50124518((E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]cinnamic ac...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PafA expressed in Escherichia coli BL-21(DE3) assessed as inhibition of pup-ylation using Mtb PanB substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed