BDBM50124364 CHEMBL3622875

SMILES Nc1ncc(s1)-c1ccncc1-c1ccccc1Cl

InChI Key InChIKey=DBAQXRPFHQUQMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124364   

TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124364(CHEMBL3622875)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124364(CHEMBL3622875)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LIMK1 in human ZR75-1 cells assessed as inhibition of cofilin phosphorylation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed