BDBM50124109 (Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-(3,5-dichloro-pyridin-4-ylmethoxy)-phenyl]-acrylic acid::CHEMBL167961

SMILES OC(=O)C(\NC(=O)c1cccnc1Cl)=C\c1ccc(OCc2c(Cl)cncc2Cl)cc1

InChI Key InChIKey=PMBIASLVECKUIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124109   

TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124109((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124109((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed