BDBM50123803 CHEMBL3623375

SMILES CN(C)CCCNC(=O)c1csc2nc(cn12)-c1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1

InChI Key InChIKey=VBYMFAOTZHNONG-UHFFFAOYSA-N

Data  50 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 50 hits for monomerid = 50123803   

TargetSerine/threonine-protein kinase PAK 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PAK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ErbB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant EphB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetMyotonin-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DMPKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant TrkBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant Rsk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant Plk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PKD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PKCmuMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PAK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant IRE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant IGF-1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human recombinant Pim1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CaMK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant BmxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AxlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant Aurora-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AMPKalpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ArgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 986nMAssay Description:Inhibition of human recombinant RetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant c-RAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human recombinant KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant Flt4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of human recombinant Flt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant FmsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 294nMAssay Description:Inhibition of human recombinant ckitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant Aurora-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed