BDBM50123695 6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-methoxy-phenyl)-hexan-1-one::CHEMBL159022

SMILES COc1ccccc1C(=O)CCCCCN1CCN(CC1)c1noc2ccccc12

InChI Key InChIKey=VRSNKCQWIMHWFX-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50123695   

Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to the rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  3.94nMAssay Description:Binding affinity of compound was tested for Dopamine receptor D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  9.03nMAssay Description:Binding affinity of compound was tested for 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  54.9nMAssay Description:Binding affinity of compound was tested for Dopamine receptor D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  78.1nMAssay Description:Binding affinity of compound was tested for Dopamine receptor D2LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  147nMAssay Description:Binding affinity of compound was tested for Sigma receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  175nMAssay Description:Binding affinity to the rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50123695(6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-me...)
Affinity DataKi:  4.30E+3nMAssay Description:Binding affinity of compound was tested for Sigma receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed