BDBM50122839 CHEMBL106227::[3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimethyl-ammonium

SMILES CCCCCCCCCCCCCCNC(=O)N[C@H](CC([O-])=O)C[N+](C)(C)C

InChI Key InChIKey=BMZYTDRMCBZVNH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50122839   

TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
Sigma Tau Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 4.34E+4nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, liver isoform(Rat)
Sigma Tau Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I from rat liver mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human CPT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
Sigma Tau Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 1.45E+3nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 2, mitochondrial(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 380nMAssay Description:Inhibition of rat CPT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human CPT1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, liver isoform(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed