BDBM50122762 4-Methyl-2-phenylethynyl-thiazole::CHEMBL65417

SMILES Cc1csc(n1)C#Cc1ccccc1

InChI Key InChIKey=DEGFQKLFNAFRBC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50122762   

TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122762(4-Methyl-2-phenylethynyl-thiazole | CHEMBL65417)
Affinity DataIC50: 13nMAssay Description:Tested in vitro against human recombinant Metabotropic glutamate receptor 5 stably expressed in LtK cells by [Ca2+] flux assay using glutamate as ant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122762(4-Methyl-2-phenylethynyl-thiazole | CHEMBL65417)
Affinity DataKi:  32nMAssay Description:Tested for displacement of [3H]3-methoxy-5-(pyridin-2-ylethynyl) pyridine from Metabotropic glutamate receptor 5 in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed