BDBM50121210 CHEMBL3622374

SMILES Nc1ccccc1NC(=O)c1ccc(cc1)-c1cn(CCc2ccsc2)nn1

InChI Key InChIKey=LBLSLSOENGWIHL-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50121210   

TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of recombinant human full length C-terminal GST-tagged HDAC1 expressed in baculovirus Sf9 insect cells using HDAC Glo I/II substrate by Ki...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 2(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNuclear receptor corepressor 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant full-length C-terminal GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His-tagged HDAC6 expressed in insect cells using Fluor de Lys as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human full length C-terminal GST-tagged HDAC4 (627 to end residues) expressed in baculovirus Sf9 insect cells using HDAC cl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin) using Fluoro-Substrate Peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system using Fluor de Lys as sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC5 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC (unknown origin) using Fluoro-Substrate Peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Washington University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human KDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of human KDAC3 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human KDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human KDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC6 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed