BDBM50119195 CHEMBL317003::{1-[4-(4-{[(R)-2-Hydroxy-2-(4-hydroxy-3-methanesulfonylamino-phenyl)-ethylamino]-methyl}-piperidine-1-sulfonyl)-phenyl]-1H-indol-3-yl}-acetic acid

SMILES CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNCC1CCN(CC1)S(=O)(=O)c1ccc(cc1)-n1cc(CC(O)=O)c2ccccc12

InChI Key InChIKey=QUXVAAUXWISJKB-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119195   

TargetBeta-1 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119195({1-[4-(4-{[(R)-2-Hydroxy-2-(4-hydroxy-3-methanesul...)
Affinity DataEC50:  30nMAssay Description:Beta-1 adrenergic receptor agonist activity as increased cAMP levels in CHO cells expressing human Beta-1-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119195({1-[4-(4-{[(R)-2-Hydroxy-2-(4-hydroxy-3-methanesul...)
Affinity DataEC50:  30nMAssay Description:Beta-2 adrenergic receptor agonist activity as increased cAMP levels in CHO cells expressing human Beta-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119195({1-[4-(4-{[(R)-2-Hydroxy-2-(4-hydroxy-3-methanesul...)
Affinity DataEC50:  11nMAssay Description:Beta-3 adrenergic receptor agonist activity as increased cAMP levels in CHO cells expressing human Beta-3-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119195({1-[4-(4-{[(R)-2-Hydroxy-2-(4-hydroxy-3-methanesul...)
Affinity DataKi:  180nMAssay Description:Binding affinity of compound against Beta-2 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119195({1-[4-(4-{[(R)-2-Hydroxy-2-(4-hydroxy-3-methanesul...)
Affinity DataKi:  240nMAssay Description:Binding affinity of compound against Beta-1 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed