BDBM50118763 2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lambda*6*-thieno[2,3-c]thiopyran-3-carboxylic acid::2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-thieno[2,3-c]thiopyran-3-carboxylic acid::CHEMBL343587

SMILES OC(=O)C(=O)Nc1sc2CS(=O)(=O)CCc2c1C(O)=O

InChI Key InChIKey=RKVURUSXNLORGI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118763   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118763(2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lam...)
Affinity DataKi:  6.03E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118763(2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lam...)
Affinity DataKi:  6.09E+3nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118763(2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lam...)
Affinity DataKi:  6.10E+3nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118763(2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lam...)
Affinity DataKi:  3.22E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed