BDBM50118157 CHEMBL128635::[1-(1-Methyl-cyclopropyl)-ethyl]-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester;C2H2O4

SMILES CC(NC(=O)OCCCc1cnc[nH]1)C1(C)CC1

InChI Key InChIKey=YOPFEILWVOUSFH-UHFFFAOYSA-N

Data  2 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118157   

TargetHistamine H2 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50118157([1-(1-Methyl-cyclopropyl)-ethyl]-carbamic acid 3-(...)
Affinity DataKd: >1.00E+5nMAssay Description:The compound was evaluated for pA2 at Histamine H2 receptor of guinea pig atriumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50118157([1-(1-Methyl-cyclopropyl)-ethyl]-carbamic acid 3-(...)
Affinity DataKd:  15.8nMAssay Description:Receptor profile was evaluated at Histamine H3 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50118157([1-(1-Methyl-cyclopropyl)-ethyl]-carbamic acid 3-(...)
Affinity DataKd:  1.58E+5nMAssay Description:Receptor profile was evaluated at Histamine H1 receptor of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50118157([1-(1-Methyl-cyclopropyl)-ethyl]-carbamic acid 3-(...)
Affinity DataKi:  5.10nMAssay Description:In vitro Histamine H3 receptor antagonist activity in synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50118157([1-(1-Methyl-cyclopropyl)-ethyl]-carbamic acid 3-(...)
Affinity DataKi:  6nMAssay Description:In vitro inhibition of binding of [125I]iodoproxyfan against human Histamine H3 receptor stably transfected on CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed