BDBM50117939 (+)1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL126913

SMILES [O-][n+]1ccc(CC(=O)N2CCC(CC2)[C@@H]2c3ccc(Cl)cc3CCc3cc(Br)cnc23)cc1

InChI Key InChIKey=MOCUABRQFZUWQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117939   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117939((+)1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,...)
Affinity DataIC50: 34nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed