BDBM50117794 CHEMBL314954::N-(4'-Chloro-biphenyl-4-ylmethyl)-N-(2-dimethylamino-ethyl)-2-[2-(4-fluoro-benzylsulfanyl)-5-(2-methoxy-pyrimidin-5-ylmethyl)-4-oxo-4H-pyrimidin-1-yl]-acetamide

SMILES COc1ncc(Cc2cn(CC(=O)N(CCN(C)C)Cc3ccc(cc3)-c3ccc(Cl)cc3)c(SCc3ccc(F)cc3)nc2=O)cn1

InChI Key InChIKey=IZQNPOJPVTXOGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117794   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50117794(N-(4'-Chloro-biphenyl-4-ylmethyl)-N-(2-dimethylami...)
Affinity DataIC50: 0.200nMAssay Description:Steady state and transient kinetics to a freely reversible, non-covalently bound, human recombinant Phospholipase A2 (rhLp-PLA2) was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed