BDBM50117729 3-Isobutyl-8-{5-[4-(2-methoxy-ethyl)-piperazine-1-sulfonyl]-2-propoxy-phenyl}-1-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL89670

SMILES CCCOc1ccc(cc1-c1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1)S(=O)(=O)N1CCN(CCOC)CC1

InChI Key InChIKey=IAIPGQGMDVQDAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117729   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117729(3-Isobutyl-8-{5-[4-(2-methoxy-ethyl)-piperazine-1-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117729(3-Isobutyl-8-{5-[4-(2-methoxy-ethyl)-piperazine-1-...)
Affinity DataIC50: 91nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed