BDBM50117335 4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-piperazine-1-carboxylic acid [4-(4-bromo-phenoxy)-phenyl]-amide::CHEMBL125805

SMILES COCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccc(Br)cc4)cc3)c2cc1OCCOC

InChI Key InChIKey=ANFWAIIWFNOPFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117335   

TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117335(4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117335(4-[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-pip...)
Affinity DataIC50: 190nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed