BDBM50117257 1-hydroxy-3-(methyl(3-phenylpropyl)amino)propane-1,1-diyldiphosphonic acid::CHEMBL54537::{1-Hydroxy-3-[methyl-(3-phenyl-propyl)-amino]-1-phosphono-propyl}-phosphonic acid

SMILES CN(CCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=CCUVTLJATBXQHJ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50117257   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50117257({1-Hydroxy-3-[methyl-(3-phenyl-propyl)-amino]-1-ph...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50117257({1-Hydroxy-3-[methyl-(3-phenyl-propyl)-amino]-1-ph...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50117257({1-Hydroxy-3-[methyl-(3-phenyl-propyl)-amino]-1-ph...)
Affinity DataIC50: 2.60nMAssay Description:Negative logarithm of inhibitory concentration against bone resorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50117257({1-Hydroxy-3-[methyl-(3-phenyl-propyl)-amino]-1-ph...)
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50117257({1-Hydroxy-3-[methyl-(3-phenyl-propyl)-amino]-1-ph...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed