BDBM50116289 2-[(1-Benzenesulfonyl-pyrrolidine-2-carbonyl)-amino]-3-(2',6'-dimethoxy-biphenyl-4-yl)-propionic acid::CHEMBL69035

SMILES COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2)C(O)=O)cc1

InChI Key InChIKey=UWDSAWYVWRSKPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116289   

TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116289(2-[(1-Benzenesulfonyl-pyrrolidine-2-carbonyl)-amin...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [125I]MAdCAM-Ig binding to human integrin alpha4-beta7 of RPMI-8866 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116289(2-[(1-Benzenesulfonyl-pyrrolidine-2-carbonyl)-amin...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of [125I]VCAM-Ig binding to human integrin alpha4-beta1 (VLA-4) of Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed