BDBM50115908 CHEMBL412448::N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benzamide

SMILES Cc1cccc(C(=O)Nc2ccc(cc2)C(N)=N)c1O

InChI Key InChIKey=LCZHEVMEFIWLIR-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50115908   

TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataKi:  3.90E+3nMAssay Description:Activation of plasminogenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed