BDBM50114843 CHEMBL3609758

SMILES COc1nc(ncc1-c1cn(nn1)C1CCc2c(F)cccc2N(CC(F)(F)F)C1=O)-n1cnc(C)c1

InChI Key InChIKey=PUPGDBNPENFDOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114843   

LigandPNGBDBM50114843(CHEMBL3609758)
Affinity DataIC50: 1.64E+3nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
LigandPNGBDBM50114843(CHEMBL3609758)
Affinity DataIC50: 260nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing APP C-terminal fragment SPA4CT assessed as inhibition of intracellular amyloid be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed