BDBM50114263 ((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-1-cyclohexylmethyl-2-oxo-ethylamino)-acetic acid; compound with ditrifluoro-acetic acid::CHEMBL208140

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2C=CCN2C(=O)[C@@H](CC2CCCCC2)NCC(O)=O)s1

InChI Key InChIKey=BUGKCANFLDYYKD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50114263   

TargetProthrombin(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 3.60nMAssay Description:In vitro Inhibitory concentration against ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 328nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 70nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Basf

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed