BDBM50113584 (E)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::(Z)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::3-(3-carbamimidoyl-phenyl)-2-fluoro-but-2-enoic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL286915

SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N

InChI Key InChIKey=YSVRMVCVENRWPF-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50113584   

TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113584(3-(3-carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113584(3-(3-carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibitory activity against Factor IIa (serine protease) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113584(3-(3-carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 259nMAssay Description:Inhibitory activity against trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113584(3-(3-carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration to coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Portola Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113584(3-(3-carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataKi:  530nMAssay Description:Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed