BDBM50112342 CHEMBL3609312

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OCC(C)C)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O

InChI Key InChIKey=ZGZYRKVUCUHVCM-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112342   

TargetBromodomain-containing protein 4(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50112342(CHEMBL3609312)
Affinity DataKd:  73nMAssay Description:Binding affinity to BRD4 (unknown origin) by isothermal calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50112342(CHEMBL3609312)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of kinase tracer 236 from human N-terminal GST-tagged ALK F1174L mutant (1058 to 1620 residues) after 60 mins by LanthaScreen Eu--kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50112342(CHEMBL3609312)
Affinity DataKi:  29nMAssay Description:Binding affinity to BRD4 (unknown origin) expressed in Escherichia coli BL21 after 1 hr by proprietary competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed