BDBM50112314 2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-methyl-ethyl]-benzoyl}-methyl-amino)-pentanedioic acid::CHEMBL60639

SMILES CC(Cc1coc2nc(N)cc(N)c12)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O

InChI Key InChIKey=RZADSRPQWMYEEU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50112314   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 3.60E+5nMAssay Description:Inhibition of rh thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 420nMAssay Description:Inhibition of rh dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Escherichia coli thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50112314(2-({4-[2-(4,6-Diamino-furo[2,3-b]pyridin-3-yl)-1-m...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed