BDBM50112172 CHEMBL3608427

SMILES [Cl-].Nc1nc(N)c(nc1Cl)C(=O)N[C@H]1CCC[N+](CCCc2ccc(OCC(=O)NCCCO)cc2)(CCCc2ccc(OCC(=O)NCCCO)cc2)C1

InChI Key InChIKey=DDNJBCVKJFTXST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50112172   

TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112172(CHEMBL3608427)
Affinity DataIC50: 13nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed