BDBM50112133 CHEMBL3609861::US9464044, 71

SMILES CC(C)(NS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O

InChI Key InChIKey=UBAPBKDXKUTATP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112133   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112133(US9464044, 71 | CHEMBL3609861)
Affinity DataIC50: 0.600nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112133(US9464044, 71 | CHEMBL3609861)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112133(US9464044, 71 | CHEMBL3609861)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112133(US9464044, 71 | CHEMBL3609861)
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed