BDBM50112127 CHEMBL3608407::US9464044, 76

SMILES CC(C)(NS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(CO)(C3)C2

InChI Key InChIKey=KNSQRFXJCMPXOL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112127   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112127(US9464044, 76 | CHEMBL3608407)
Affinity DataIC50: 2.40nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112127(US9464044, 76 | CHEMBL3608407)
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112127(US9464044, 76 | CHEMBL3608407)
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed