BDBM50110300 CHEMBL15056::N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8-tetrahydroacridin-9-amine::{2-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-ethyl}-(1,2,3,4-tetrahydro-acridin-9-yl)-amine; Oxalic acid

SMILES C(COc1ccc(CCNc2c3CCCCc3nc3ccccc23)cc1)CN1CCCCC1

InChI Key InChIKey=IBPWGZKZWJYGLA-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50110300   

TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110300(N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8...)
Affinity DataIC50: 48nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50110300(N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110300(N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8...)
Affinity DataKi:  0.330nMAssay Description:Affinity for displacement of [125I]iodoproxyfan from human histamine H3 receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50110300(N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed