BDBM50109931 (+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-ynylamino}-5,6,7,8-tetrahydronaphthalen-2-ol::(-)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-ynylamino}-5,6,7,8-tetrahydronaphthalen-2-ol::7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL157293

SMILES Oc1ccc2CCC(Cc2c1)N(CCCCN1CCN(CC1)c1ccccc1)CC#C

InChI Key InChIKey=LXFPKJLLIWPMEU-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50109931   

TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  1.40nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  32.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  32.9nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931(7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-prop-2-ynyl...)
Affinity DataKi:  68nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed