BDBM50109927 (+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol::(-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol::7-{[4-(4-Phenyl-piperazin-1-yl)-butyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL155826

SMILES CCCN(CCCCN1CCN(CC1)c1ccccc1)C1CCc2ccc(O)cc2C1

InChI Key InChIKey=RURKEKYFHBYLDY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50109927   

TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  3.80nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  19.3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  19.4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((-)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  114nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed