BDBM50109389 1-Phenethyl-piperidine::1-phenethylpiperidine::CHEMBL75228::N-(2-phenylethyl)piperidine::N-phenethylpiperidine

SMILES C(Cc1ccccc1)N1CCCCC1

InChI Key InChIKey=DBDVAKGHPZJLTH-UHFFFAOYSA-N

Data  9 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50109389   

TargetAmine oxidase [flavin-containing] A(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataIC50: 7.57E+5nMAssay Description:Inhibition of human recombinant MAOA expressed in insect cells using kynuramine substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataIC50: 7.62E+5nMAssay Description:Inhibition of human recombinant MAOB expressed in insect cells using benzylamine hydrochloride as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenates after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  89nMAssay Description:Binding affinity for sigma-1 receptor by displacing [3H]-(+) pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  309nMAssay Description:In vitro binding affinity at opioid sigma-1 receptor in guinea pig brain membranes by (+)-[3H]pentazocine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  309nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  595nMAssay Description:Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi: >700nMAssay Description:In vitro binding affinity at serotonin 5-hydroxytryptamine 3 receptor in rat cortex by [3H]granisetron displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  3.68E+6nMAssay Description:Competitive inhibition of human recombinant MAO-A assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50109389(N-phenethylpiperidine | N-(2-phenylethyl)piperidin...)
Affinity DataKi:  1.21E+5nMAssay Description:Competitive inhibition of human recombinant MAO-A assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed