BDBM50107790 4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-benzenesulfonylamino-indan-5-yl)-amide::CHEMBL357886

SMILES FC(F)(F)c1ccc(cc1)-c1ccccc1C(=O)Nc1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=SPCXYBUWDJJYRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107790   

TargetMicrosomal triglyceride transfer protein large subunit(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107790(4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-b...)
Affinity DataIC50: 105nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApolipoprotein B-100(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107790(4'-Trifluoromethyl-biphenyl-2-carboxylic acid (2-b...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed