BDBM50107783 CHEMBL343837::{5-[(4'-Chloro-4,6-dimethyl-biphenyl-2-carbonyl)-amino]-indan-2-yl}-carbamic acid methyl ester

SMILES COC(=O)NC1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(Cl)cc3)cc2C1

InChI Key InChIKey=QEEDOZCUASXVAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107783   

TargetMicrosomal triglyceride transfer protein large subunit(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107783({5-[(4'-Chloro-4,6-dimethyl-biphenyl-2-carbonyl)-a...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetApolipoprotein B-100(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107783({5-[(4'-Chloro-4,6-dimethyl-biphenyl-2-carbonyl)-a...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed