BDBM50107562 CHEMBL168119::N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-2-(4-hydroxy-piperidin-1-yl)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-4-tert-butyl-benzenesulfonamide

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOc1ncc(Br)cn1)N1CCC(O)CC1

InChI Key InChIKey=RUOMKRIFLYCNKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107562   

TargetEndothelin-1 receptor(Pig)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107562(N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-2-(4-h...)
Affinity DataIC50: 0.00250nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Rat)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107562(N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-2-(4-h...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin B receptor (ETB-receptor) in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed